What Are The Target Organ Of Vinyl Chloride
Vinyl chloride monomer page 1 of 8 sds no.
What are the target organ of vinyl chloride. The target organs for vc now clearly in. Synonyms trade names chloroethene chloroethylene ethylene monochloride monochloroethene monochloroethylene vc vcm vinyl chloride monomer vcm. The reader is referred to section 3 2 discussion of health effects by route of exposure for additional information on other effects. The following is a target organ categorization of effects which may occur from exposure to hazardous chemicals including examples of signs and symptoms and.
12 10 2017 01 identification of the substance preparation and the company undertaking product name vinyl chloride monomer sds no. Occupational exposure to vinyl chloride has been associated with reduced sexual function in both sexes and gynecological effects in women makarov 1984. There may be a latent period of hours to days between exposure and symptom onset. Noncancerous hepatotoxicity and carcinogenicity of vinyl chloride are discussed in greater detail below.
Vinyl chloride is an organochloride with the formula h 2 c chcl that is also called vinyl chloride monomer vcm or chloroethene this colorless compound is an important industrial chemical chiefly used to produce the polymer polyvinyl chloride pvc. In 1974 vinyl chloride vc was first reported in the open scientific literature to induce angiosarcoma of the liver both in humans and in animals. At room temperature vinyl chloride is a colorless highly flammable potentially explosive gas. The primary route of vinyl chloride exposure is inhalation.
About 13 billion kilograms are produced annually. Accidental ingestion may be possible when eating or smoking with contaminated hands. Target organs liver central nervous system blood respiratory system lymphatic system cancer site liver cancer. Additional research has now demonstrated the carcinogenicity of vc to other organs and at lower concentrations.
Target organ effect the target organs and potential effects of vinyl chloride exposure include. It is shipped and handled this way. It has a faint sweet odor. The liver appears to be the most sensitive target organ of vinyl chloride.
When confined under high pressure in special containers vinyl chloride exists in a liquefied state. Target organ toxins are chemicals that can cause adverse effects or disease states manifested in specific organs of the body. The odor threshold for vinyl chloride is about 3 000 ppm in air depending on the individual. Table 1 target organs and potential effects of vinyl chloride exposure target organ effect.
Qatar vinyl company ltd. Box 24440 doha state of qatar. Makarov et al 1984. 003 manufacturer emergency telephone no.
The cns is the primary target of vinyl chloride acute toxicity.